منابع مشابه
DNA Makes RNA Makes Innate Immunity
Microbial DNA in the cytosol induces production of interferon-beta (IFN-beta) and an innate immune response. Chiu et al. (2009) now implicate cytosolic DNA-dependent RNA polymerase III as the DNA sensor linking DNA release by pathogenic bacteria and viruses in the host cell cytosol to IFN-beta production and innate immunity.
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A mutation that disrupts post-transcriptional gene silencing in Neurospora crassa has been found to affect the homologue of a plant-encoded RNA-dependent RNA polymerase. This enzyme may produce a specificity determinant of gene silencing and mediate an epigenetic conversion at the RNA level.
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In a path-breaking article, Wade Huntley (1996) reinterpreted Immanuel Kant’s pacific union as a systemic phenomenon. Huntley’s argument spawned a new wave of inquiry into the evolutionary expansion of the democratic peace, with several empirical studies finding a positive relationship between global democracy and systemic peace (e.g. Crescenzi and Enterline 1999; Gleditsch and Hegre 1997; Kade...
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The recently determined crystal structure of the Ku heterodimer, in both DNA-bound and unbound forms, has shed new light on the mechanism by which this protein fulfills its key role in the repair of DNA double-strand breaks.
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Although there has been some empirical research on earworms, songs that become caught and replayed in one’s memory over and over again, there has been surprisingly little empirical research on the more general concept of the musical hook, the most salient moment in a piece of music, or the even more general concept of what may make music ‘catchy’. Almost by definition, people like catchy music,...
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ژورنال
عنوان ژورنال: The Biochemist
سال: 2002
ISSN: 0954-982X,1740-1194
DOI: 10.1042/bio02406039